CV
CURRENT POSITION
- Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), Rome, IT
Scientific Researcher, 2017-Present - ELIXIR-IIB (http://elixir-italy.org)
ELIXIR Italy Training Coordinator, 2014-Present - University of Bologna, Master in Bioinformatics, Bologna, IT
Adjunct professor, 2016-Present
NATIONAL SCIENTIFIC QUALIFICATION
- Molecular Biology (05/E2 - SSD BIO/11) - Associate Professor
- Applied Physics (02/B3 - SSD FIS/07) - Associate Professor
- Biochemistry (05/E1 – SSD BIO/10) - Associate Professor
EDUCATION
- Università di “Tor Vergata”, Roma, IT
PhD, Cellular and Molecular Biology, 2003
Dissertation: “Protein structural study for the optimization and analysis of sequence functional motifs”
Supervisor: Prof. Manuela Helmer-Citterich - Sapienza Università, Roma, IT
Master Degree, Physics, 1997
Dissertation: “Analytical study of the Sherrington and Kirkpatrick spin-glass model”
Supervisor: Prof. Giorgio Parisi - Université Paris Diderot – Paris 7, Paris, FR
Erasmus programme, Dept. of Mathematics, 1994-1995
ATTENDANCE TO TRAINING COURSES
- EMBL-EBI, Hinxton, UK
GOBLET/ELIXIR “Metagenomics Hackathon”, April 2016 - CSC, Espoo, Helsinki, FI
ELIXIR-EXCELERATE workshop “Using clouds and VMs in bioinformatics training”, May 2016 - University of Lausanne, Lausanne, CH
Software and Data Carpentry course on “Instructor Training”, January 2016 - Wellcome Trust Sanger Institute, Hinxton, UK
BioMalPar (FP6 Malaria Initiative) course on “Introduction to Plasmodium Bioinformatics”, August 2005 - Università di Bologna, Bologna, IT
4th Bologna Winter School “Hot Topics in Structural Genomics”, February 2003 - **Institute for Scientific Interchange foundation, Villa Gualino, Torino, IT **
Euroconference on “Protein folding and structure prediction”, June 1998
RESEARCH EXPERIENCE
- - Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), Bari, IT
Research Associate, 2016
Topics:- Design, organisation and delivery of bioinformatics training courses
- Train the Trainer activities
- Learning theories and how they can be translated into teaching practices
- Cognitive science/Educational psychology
- Sapienza Università, Roma, IT
Research Associate (RTD), 2009-2015
Topics:- Therapeutic targets and their inhibitors, host-pathogen interactions using state-of-the art tools in computational biology.
- Modelling of biological systems. Development of bioinformatics resources. Building pipelines.
- Sapienza Università, Department of Biochemical Sciences, Roma, IT
Postdoctoral fellow, 2007-2009
Topics:- Protein structure, function and disease using state-of-the art tools in computational biology
- Development of bioinformatics methodologies and resources. Building pipelines.
- Università di Bologna, Department of Experimental Biology of Evolution, Bologna, IT
Postdoctoral fellow, 2006-2007
Topics:- Protein structure and function; Protein phosphorylation; Linear motifs.
- Development of bioinformatics methodologies and resources; Neural networks.
- *Università di “Tor Vergata”, Department of Biology, Roma, IT **
*Postdoctoral fellow, 2003-2006
Topics:- Protein structure and function; PTM, modular domains and signalling; functional motifs.
- Development of bioinformatics methodologies and resources.
GRANTS AND AWARDS
- Sapienza Università research grant for the “Characterisation of Plasmodium falciparum antigens triggering autoimmune response”, 2013
- Sapienza Università research grant for the “Identification of molecular targets in malaria and schistosomiasis and characterisation of their interactions with candidate inhibitors”, 2011
- Telethon awards for the work in the project “Multi-centre bioinformatics project for a systematic investigation of gene expressed in human skeletal muscle”, 2005 and 2002
- Genes, Protein & Computer VI Conference best poster award, Chester College, Chester, 2000
ACADEMIC TEACHING AND ADVISING EXPERIENCE
- Università di Bologna, School of Science, MD in Bioinformatics, Bologna, IT
Head teaching fellow, Module 3 (on Protein Interactions, 20h) in the Laboratory of Bioinformatics 1 course, 2015-2016 - Sapienza Università, MD in Engineering of Nanotechnology, Roma, IT
Head teaching fellow, “Macromolecular structures” (6 CFU), 2010-2015 - Sapienza Università, MD in Physics of Biosystems, Roma, IT
*Head teaching fellow8, “Biochemistry” (6 CFU), 2011-2012 - Università di “Tor Vergata”, MD in Bioinformatics, Roma, IT
Head teaching fellow, “Computational methods for Biology” (6 CFU), 2005-2010 - Università di “Tor Vergata”, MDs in Cellular and Molecular Biology, in Human Biology, and in Bioinformatics, Roma, IT
Teaching assistant, “ Molecular Bioinformatics”, 2003-2005 - Università di “Tor Vergata”, B.Sc. in Cellular and Molecular Biology & B.Sc. in Human Biology, Roma, IT
Teaching assistant, “Bioinformatics”, 2002-2003
TRAINING EXPERIENCE
- ELIXIR-IIB practical course, University of Bari, Bari, Italy
Organiser and instructor, “Python for Life Scientists”, 26-30 September 2016 - RDA-CODATA Research Data Science Summer School, ICTP, Trieste, Italy
Lead Instructor, “Software Carpentry module”, 01-04 Aug 2016 - ELIXIR-EXCELERATE Train the Trainer course, IGC, Oeiras, Portugal
Organiser and instructor, 10-15 Jul 2016 - Scientific School on “Computational modeling for Life Sciences”, Sardinian Scientific and Technological Park, Pula (CA), Italy
Invited speaker and Instructor, 06-10 June 2016 - RNA-seq data analysis workshop, University of Naples Federico II in collaboration with ELIXIR-IIB, Naples, Italy
Invited speaker, June 6th-10th, 2016 - ELIXIR-IIB practical course, CNR, Napoli, Italy
Organiser and instructor, “NGS for evolutionary biologists: from basic scripting to variant calling”, 2-5 May 2016 - EMBO practical course, Budapest, Hungary
Instructor, “Introduction to Linux command line” and “ Structure and interfaces of PPIs “ in the EMBO practical course on “Computational analysis of protein-protein interactions: Sequences, networks and diseases” (http://events.embo.org/16-protein-protein/), 30th May-4th Jun 2016 - ELIXIR-IIB practical course, Università di Bologna, Bologna, IT
Organiser and instructor, “Protein networks and systems biology”, 14-18 Dec 2015 - ELIXIR-IIB practical course, CINECA Auditorium, Rome, IT
Organiser and instructor, “NGS for evolutionary biologists: from basic scripting to variant calling”, 23-27 Nov 2015 - ELIXIR-IIB practical course, CINECA Auditorium, IT
Organiser and instructor, “Gene expression profiling with HTS: RNA-Seq data analysis”, 19-22 Oct 2015 - PhD School in Biology and Molecular Medicine Training course, Sapienza Università, Rome, IT
Organiser and instructor, “Next Generation Sequencing data analysis”, 5-7 Oct 2015 - EMBO practical course, TGAC, Norwich, UK
Instructor, “Structure of PPIs and interfaces of PPIs, predicting globular 3D structure” in the EMBO Practical Course: Computational Analysis of Protein-Protein Interactions: From Sequences to Networks (http://events.embo.org/15-protein-protein/), 28th Sept- 3rd Oct 2015 - 2nd level Master in Bioinformatics: Biomedical and Pharmaceutical applications, Sapienza Università, Rome, IT
Instructor, “Programming and algorithms for Bioinformatics” (24h), 2014 and 2015 - GTPB practical course, Instituto Gulbenkian de Ciência, Oeiras, PT
Instructor, “Bioinformatics using Python for Biologists” (40h each year), 2010-2016 - TGAC practical course, Norwich, UK
Instructor, “Python for Life Scientists” (40h each year), 2013-2015 - Institut Pasteur practical course, Tunis, TN
Instructor, “Proteomics and drug design” (20h), April 2012 - Università di “Tor Vergata” post-graduate training course, Roma, IT
Instructor, “Bioinformatics applications” (30h), 2000
RELATED PROFESSIONAL EXPERIENCE
- ELIXIR-IIB Training Coordinator Coordinates the ELIXIR Italian node training activities. ELIXIR (http://www.elixir-europe.org) is a distributed sustainable European infrastructure for life science information, supporting life science research and its translation to medicine, agriculture, bioindustries and society. ELIXIR-ITA, the Italian node of ELIXIR, is a Joint Research Unit with 17 member institutions (11 Universities, CNR, CRS4, INFN, CINECA, FONDAZIONE EDMUND MACH), 2014-present
- ELIXIR-IIB Technical Coordinator for Sapienza Università
Coordinates ELIXIR-ITA research support activities for - Sapienza Univeristà, Rome, 2014-present - ELIXIR-EXCELERATE Train the Trainer subtask leader (WP11, Training platform)
Coordinates the WP11 Train the Trainer subtask activities for the ELIXIR-EXCELERATE EC funded project (2015-2018) Italian representative in the ELIXIR taskforce on “Best practices in software development”. - ELIXIR’s liaison to the EU Project: “EDISON, building the data science profession”, 2016-present.
- Secretary of the Global Organisation for Bioinformatics Learning Education and Training (GOBLET, http://www.mygoblet.org), 2012-2013.
- Chair of the Bioinformatics Training Network (BTN, http://www.biotnet.org), 2011-2013.
- Italian representative in the “Training portal” and “e-learning and training” ELIXIR task forces, 2014-present. Data/Software Carpentry certified Instructor (http://software-carpentry.org), since Jan 2016.
- Member of the PC for the following conferences: ECCB (European Conference on Computational Biology); ISMB (International Conference on Intelligent Systems for Molecular Biology); BIRD (International Conference on Bioinformatics Research and Development); BIOINFORMATICS (http://www.bioinformatics.biostec.org); NETTAB (Network Tools and Applications in Biology).
- Organisation of practical courses, workshops and conferences:
- Local organiser for the NETTAB 2016 workshop on “Reproducibility, standards and SOP in bioinformatics”, CNR, Rome, IT, 100 participants, October 2016.
- Co-organised the NETTAB 2016 satellite Goblet/ELIXIR-IIB joint tutorial on “Train the Trainer”, CNR, Rome, IT, expected 20 participants, October 2016.
- Co-organised the Education & Training special session of the NETTAB 2016 Workshop, CNR, Rome, IT, October 2016.
- Co-organised the practical course on “Python for Life Scientists”, University of Bari, Bari, IT, expected 24 participants, September 2016.
- Co-organised the practical course on “Exome analysis using Galaxy”, University of Milano-Bicocca, Milano, IT, expected 24 participants, September 2016.
- Co-organised the 2nd ELIXIR-EXCELERATE “Train the Trainer” course, IGC, Oeiras, PT, (limited to) 8 participants, July 2016.
- Co-organised the BITS 2016 satellite workshop on “Effective academic teaching”, University of Salerno, Fisciano (SA), IT, 20 participants, June 2016.
- Co-organised and co-chaired the round table on “Teaching Bioinformatics: state-of-the-art and new ideas” at the BITS 2016 conference, University of Salerno, Fisciano (SA), IT, June 2016.
- Co-organised the 1st ELIXIR-EXCELERATE “Train the Trainer” course, University of Cambridge, Cambridge, UK, (limited to) 10 participants, May 2016.
- Co-organised the ELIXIR-IIB practical course on “NGS for evolutionary biologists: from basic scripting to variant calling”, CNR, Naples, IT, 24 participants, May 2016.
- Co-chaired the ELIXIR-EXCELERATE “Train the Trainer” framework workshop, EBI, Hinxton, UK, January 2016.
- Co-organised the ELIXIR-IIB practical course on “Protein networks and systems biology”. Università di Bologna, Bologna, IT, 24 participants, December 2015.
- Co-organised the ELIXIR-IIB practical course on “NGS for evolutionary biologists: from basic scripting to variant calling”. CINECA Auditorium, Rome, IT, 24 participants, November 2015.
- Organised the ELIXIR-IIB practical course on “Gene expression profiling with HTS: RNA-Seq data analysis”. CINECA Auditorium, Rome, IT, 24 participants, October 2015.
- Co-organised the practical course on “Next Generation Sequencing data analysis”. PhD School in Biology and Molecular Medicine (BeMM), Rome, IT, 40 participants, October 2015.
- Co-organised the practical course on “Python for Life Scientists”. The Genome Analysis Centre, Norwich, UK, 25 participants, 40h, October 2013 and April 2015.
- Co-organised the workshop: “Bioinformatics Training for Life Scientists: Showcases and Challenges from Tutors’ Perspectives”, Basel, CH, 40 participants, September 2012.
- Local organising committee member of ECCB’08 (European Conference on Computational Biology), Cagliari, Sardinia, IT, > 400 participants, September 2008.
LANGUAGES
Italian, native; English, fluent; French, fluent; German, basic
SKILLS and TECHNIQUES
- UNIX/Linux and Mac OSX administration
- Python programming
- Web programming (HTML, CGI, Django)
- R scripting for statistical analyses
- Pipeline building (NGS data analysis, data retrieval and filtering, etc.)
- Bioinformatics tools development and testing
- Relational database management systems MySQL and PostgreSQL
- Molecular graphics systems: PyMOL, Chimera, SwissPDB viewer
- Docking packages (e.g. Autodock)
- Most of the state-of-the-art tools for bioinformatics and computational biology analyses (e.g. local Blast+, ClustalW, Modeller, etc.)
- VM and Cloud computing
SELECTED INVITED TALKS
- “Ten simple rules to make your teaching more effective”, BITS 2016 Conference, University of Salerno, Fisciano (SA), IT, June 2016
- “Role of structure-based homology modeling in biomolecular sciences”, Scientific School on “Computational modeling for Life Sciences”, Sardinian Scientific and Technological Park, Pula (CA), IT, June 2016
- “Computational approaches to the study of functional sites in biomolecules”, Università di “Tor Vergata”, Roma, IT, 2014
- “A computational approach for the study of therapeutic targets and their inhibitors in human pathogens”, TAGC Inserm, Aix-Marseille Université, FR, 2014
- “Best practices in programming for biological data management”, The Genome Analysis Centre, Norwich, UK, 2013
- “GOBLET”, NextGenBug 31st meeting, ARK Genomics, Roslin, Edinburgh, UK, 2013
- “A structural approach to the study of therapeutical targets and their inhibitors in human pathogens”, Bi-national Israel-Italy meeting, Tel Aviv University, Israel, 2012
- “Cross-talking between human genome variations and their protein environment: a computational study”, IRB Barcelona, SP, 2009
- “Structural bioinformatics: a meeting-place for Biology and Physics”, Università di Bologna, IT, 2008
- “High-throughput protein functional annotation based upon local structure similarity”, Genome Annotation: a BioSapiens Network of Excellence Initiative. 5th European Conference on Computational Biology (ECCB), IL, 2006
- “Proteins: Structure, Function, Evolution”, IUSS (Istituto Universitario di Studi Superiori), Università di Pavia, Pavia, IT, 2001
- “The structure of Proteins”, in the Course of “Problems in Biological Evolution”; Scuola di Genetica di Cortona, Associazione Genetica Italiana (AGI), Cortona, IT, 2001